BDBM350085 3-[3-[4-[dideuterio(methylamino)methyl]phenyl]isoxazol-5-yl]-5-(4-isopropylsulfonylphenyl)pyrazin-2-amine ::BDBM50226746::US10208027, Compound II-1::US10208027, Compound II-2::US10208027, Compound II-3::US10208027, Compound II-4::US10479784, Compound IIA-7::US10822331, Cmpd II-4::US10961232, Compound IIA-7::US11787781, Compound A

SMILES CNCc1ccc(cc1)-c1cc(on1)-c1nc(cnc1N)-c1ccc(cc1)S(=O)(=O)C(C)C

InChI Key InChIKey=JZCWLJDSIRUGIN-UHFFFAOYSA-N

Data  30 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350085   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre

Curated by ChEMBL
LigandPNGBDBM350085(3-[3-[4-[dideuterio(methylamino)methyl]phenyl]isox...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed